
Protein Palmitoylation
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Cancer
Palmitoylation can inhibit oncogenic signaling providing opportunities for novel signal inhibitors as well as strategies for exploiting synthetic lethality.
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Nervous System
Palmitoylation of ion channels in the nervous system influencing memory and learning. The impact of influencing palmitoylation in the brain is completely unexplored.
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Pathogens
Viruses like Covid-19 and parasites that cause malaria require protein palmitoylation for reproduction and spread. These enzymes provide a novel strategy for intervention.