Protein Palmitoylation

  • Cancer

    Palmitoylation can inhibit oncogenic signaling providing opportunities for novel signal inhibitors as well as strategies for exploiting synthetic lethality.

  • Nervous System

    Palmitoylation of ion channels in the nervous system influencing memory and learning. The impact of influencing palmitoylation in the brain is completely unexplored.

  • Pathogens

    Viruses like Covid-19 and parasites that cause malaria require protein palmitoylation for reproduction and spread. These enzymes provide a novel strategy for intervention.